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Brown CJ et al (2009) Awakening guardian angels: drugging the p53 pathway. An extra breast (polymastia) or nipple(polythelia) may occur as an inheritable condition in about1% ofthe female population. The family comprised the consan-guineous parents and two affected children, suggesting autosomal recessive inheri-tance, even though the literature describes mainly sporadic and dominant cases [ 34 ].The work?ow included enrichment with Agilent SureSelect, sequencing on anIllumina Genome Analyzer, alignment with bwa [ 12], PCR duplicates marking withPicard [ 13], indel realignment, base-quality recalibration and variant calling withGATK [ 15], annotation with Annovar [ 16] and an in-house script for the calculationof homozygous regions using stretches of homozygous variations found in the WESdata. By extension,it is believed that hypertension control will reduce VCI,but studies supporting this are limited

By extension,it is believed that hypertension control will reduce VCI,but studies supporting this are limited. [ 106 ]depleted endogenous p63 by shRNA to investigate the transcriptional programscontrolled by p63.

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